2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well-defined
Examples of lesion in a Sentence
Recent Examples on the Web
Humans may develop temporary pruritic skin lesions.
—
Dr. John De Jong, Boston Herald, 26 Apr. 2026
Brazilian President Luiz Inácio Lula da Silva underwent surgery to remove a fairly routine skin cancer lesion, a procedure doctors said would have no impact on the 80-year-old leader’s reelection campaign.
—Daniel Carvalho, Bloomberg, 24 Apr. 2026
Kimmel began chemo and radiation, then underwent surgery to remove the cancerous lesion.
—Cara Lynn Shultz, PEOPLE, 18 Apr. 2026
Images of Al-Mousawi’s body covered in bruises and lesions on his face, feet and torso filled social media feeds.
—Jane Lytvynenko, NBC news, 17 Apr. 2026
See All Example Sentences for lesion
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Dr. John De Jong, Boston Herald, 26 Apr. 2026
Brazilian President Luiz Inácio Lula da Silva underwent surgery to remove a fairly routine skin cancer lesion, a procedure doctors said would have no impact on the 80-year-old leader’s reelection campaign.
—Daniel Carvalho, Bloomberg, 24 Apr. 2026
Kimmel began chemo and radiation, then underwent surgery to remove the cancerous lesion.
—Cara Lynn Shultz, PEOPLE, 18 Apr. 2026
Images of Al-Mousawi’s body covered in bruises and lesions on his face, feet and torso filled social media feeds.
—Jane Lytvynenko, NBC news, 17 Apr. 2026
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 28 Apr. 2026.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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