2
: an abnormal change in structure of an organ or part due to injury or disease
especially
: one that is circumscribed (see circumscribe sense 1) and well defined
Examples of lesion in a Sentence
Recent Examples on the Web
In September, Biden underwent Mohs surgery to remove skin cancer lesions—a procedure his physician said removed all cancerous tissue, requiring no further treatment.
—
Gabe Whisnant, MSNBC Newsweek, 20 Oct. 2025
The cat may have a case of conjunctivitis, the cat may have some trauma to the eye such as a corneal lesion as a result of a cat fight, or a foreign body got into the eye and is working itself out.
—Dr. John De Jong, Boston Herald, 19 Oct. 2025
CCMs are lesions in the brain that occur when the cells that make up blood vessels undergo uncontrolled growth.
—Richard J. Price, The Conversation, 15 Oct. 2025
Next, the energy is turned up for treatment to create the permanent lesion to interrupt the circuit.
—Charlotte Observer, 2 Oct. 2025
See All Example Sentences for lesion
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Gabe Whisnant, MSNBC Newsweek, 20 Oct. 2025
The cat may have a case of conjunctivitis, the cat may have some trauma to the eye such as a corneal lesion as a result of a cat fight, or a foreign body got into the eye and is working itself out.
—Dr. John De Jong, Boston Herald, 19 Oct. 2025
CCMs are lesions in the brain that occur when the cells that make up blood vessels undergo uncontrolled growth.
—Richard J. Price, The Conversation, 15 Oct. 2025
Next, the energy is turned up for treatment to create the permanent lesion to interrupt the circuit.
—Charlotte Observer, 2 Oct. 2025
See All Example Sentences for lesion
Cite this Entry
“Lesion.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lesion. Accessed 26 Oct. 2025.
Copy CitationKids Definition
lesion
noun
le·sion
ˈlē-zhən 
: a change in the structure of a bodily organ or part due to injury or disease
especially
: an injured or diseased spot or area clearly marked off from healthy tissue around it
Medical Definition
Legal Definition
lesion
noun
le·sion
ˈlē-zhən
in the civil law of Louisiana
: loss from failure to receive a threshold amount or value (as one-half market value) for immovable property conveyed or transferred by a commutative contract (as a sale or exchange)
called also lesion beyond moiety
compare unjust enrichmentEtymology
Anglo-French, damage, injury, from Latin laesio, from laedere to injure
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